Biomedical Engineering (Matsuda Lab)
As measurement systems of biological functions used for diagnostic imaging and data processing systems used for gene analysis, information systems currently serve as essential infrastructure for medical science and medical treatment. Research into medical systems requires an interdisciplinary effort that brings together the two fields denoted by the key words "information" and "bio". We are pursuing education and research relating to information systems for medical science and treatment, aimed at establishing methodologies for functional imaging of the brain and heart, and developing new measurement techniques for biophysical characteristics, through joint research projects in a wide range of fields with the Faculty of Medicine and other partners.
Professor (Graduate School of Informatics)
- MRI (Magnetic Resonance Imaging)
- Haptic Information processing
- physiological Simlation of Cardiovascular System
- Electrical and Electronic Engineering in Biomedical Applications
Yoshida Hon-machi, Sakyo-ku, Kyoto, 606-8501
E-mail: tetsu[at]i. kyoto-u.ac.jp
Associate Professor (Graduate School of Informatics)
- Biomedical Graphics/Visualization
- Computer Aided Surgery
- Medical Engineering
Faculty of Engineering Bldg No.2, Room 426
Yoshida-Honmachi, Sakyo, Kyoto, 606-8501, JAPAN
Assistant Professor (Graduate School of Informatics)
Introduction to R&D Topics
Measurement and analysis of tissue elasticity (stiffness, softness) using MRI
Information of tissue stiffness can be served as a diagnostic indicator of some diseases or biological dysfunction. We conduct research on the MRE (MR elastography) method for measuring the stiffness of tissue in vivo, which works by externally applying an oscillation to the tissue and then capturing images of the propagating waves by means of MRI.
Haptic representation of human internal organs
In VR systems like those used in surgery simulations, when conducting processes that correspond to palpation—for example, to check for tumors in internal organs—there is a need to achieve a more realistic haptics experience. This lab is pursuing research on analyzing human haptic perception characteristics and modeling the mechanical characteristics of virtual objects, by constructing a haptic information comparison system from real and virtual objects, for the purpose of simulating the real haptic sense experienced with real objects.
Construction of a morphological database of human embryo samples
Advances in the analysis of the human genome have made it necessary to clarify the relationship between the genetic information represented by the genome and the morphology expressed durnig human embryonic development. Thus, the construction of a database of morphological information on human embryo samples would serve as a valuable data resource for elucidating the actions of genes that contribute to the complex morphogenesis during embryonic development. Our lab is working on constructing a morphology database from a human embryo collection (Kyoto collection) held by Kyoto University's Congenital Anomaly Research Center. The Kyoto collection, which consists of tens of thousand of formalin-fixed samples, including both macroscopic and contiguously sliced samples, is internationally unprecedented in its scale.
Recent advances in elucidating functions of organelles within cells such as ion channels and pumps have realized the quantitative modeling of their functions. In collaboration with the Department of Physiology and Biophysics in the School of Medicine, that performs precise mathematical modeling of cardiac myocytes, our lab is working on modeling and simulating living tissues, with a particular focus on the function of the heart.